Functionalized carbon nanomaterials as nanocarriers for loading and delivery of a poorly water-soluble anticancer drug: a comparative study.

نویسندگان

  • Nanda Gopal Sahoo
  • Hongqian Bao
  • Yongzheng Pan
  • Mintu Pal
  • Mitali Kakran
  • Henry Kuo Feng Cheng
  • Lin Li
  • Lay Poh Tan
چکیده

Carbon nanomaterials such as multiwalled carbon nanotubes (MWCNTs) and graphene oxide (GO) have been functionalized by highly hydrophilic and biocompatible poly(vinyl alcohol) (PVA) for loading and delivery of an anticancer drug, camptothecin (CPT). For the first time, CPT was loaded onto MWCNT-PVA and GO-PVA through π-π interactions and its capability to kill human breast and skin cancer cells was investigated.

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عنوان ژورنال:
  • Chemical communications

دوره 47 18  شماره 

صفحات  -

تاریخ انتشار 2011